| Academic year: | 2007-2008 |
| Course code module | 1MBMW-K-022 |
| Semester: | 1st semester |
| Credits: | 6 |
| Study load (hours) | 168 |
| Theory (hours): | 35,00 |
| Practice/Exercises(hours): | 15,00 |
| Other (hours): | 5,00 |
| Part-time program: | |
| Instructor(s) | Anne Marie Van Der Linden
Marleen Verhoye
Paul Parizel
|
| Language of instruction: | English |
| Semester exam information: | semester exam in January |
| Contract restriction information: | |
1. Prerequisites
*Algemene competenties
Basic knowledge of the structure and function of the human body in terms of anatomy, histology and physiology. More specific, knowledge of the anatomy of the nervous system and the physiology of neurons and blood vessels.
Knowledge of the principles of different imaging techniques.
Basic mathematics and digital signal processing are required to understand the different image acquisitions and image reconstruction techniques.
*Sequentiality
- Biomedical imaging techniques
- Neurosciences
2. Objectives (expected learning outcomes)
The aim of this integrated theoretical/practical course is:
·
to obtain both insight and experience in different imaging techniques
·
to have knowledge of the information (anatomical, physiological, cellular, molecular) these images can provide
·
to have knowledge of the tremendous possibilities and applications of the modern imaging techniques for imaging the central nervous system
·
to have insight in the different MR and CT contrasts and MR and CT techniques both at the level of the acquisition parameters and the quantitative image processing
3. Course content
The course is considered as an integrated practical course in which the different techniques for neuroimaging are tackled. The applications, indication and medical value of all techniques for neuroimaging will be discussed and illustrated by means of literature or practical examples. Necessarily attention will be paid to the advanced image processing used in biomedical research. The course also gives insight in how image contrasts can be acquired technically and what are the underlying physiological or anatomical mechanisms for each image contrast.
- CT
-
CT contrast agents and their application in biomedical research
- Perfusion CT
- 3D techniques
- CT-angiography
- MRI
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MRI contrast agents and their use in biomedical research
-
Diffusion weighted MRI + applications of DW MRI (stroke, MS, development /degeneration white matter ..)
-
Perfusion weighted MRI +
applications of
PW MRI (ischemia, brain tumors)
-
Functional MRI for brain functioning + possibilities with fMRI with different applications
-
Flow and MR Angiography + applications
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Ultra fast Imaging + applications (use in fMRI, quantification volume brain regions)
-
Leakage of blood-brain-barrier with dynamic MRI using contrast agents
The students will be able to perform MR and CT experiments. The p
ractical course is focused on the different MR techniques and the acquired physiological parameters (obtained using customized image processing techniques).
4. Teaching method
Direct contact: LecturesPractical sessions
5. Assessment method
Exam: Oral, with written preparationMultiple choiceOpen questions
Continuous assessment: Assignments
Presentation
6. Compulsory reading – study material
Course document : Magnetic Resonance Imaging of the nervous system (Dr. M. Verhoye)
7. Recommended reading - study material
Medical Imaging Physics, 4th ed.
William R. Hendee, E. Russell Ritenour, ed. Wiley-Liss, 2002 , NY-ISBN 0-471-38226-4
MRI from picture to proton, D.W. McRobbie, E.A. Moore, M.J. Graves and M.R. Prince Cambridge University Press, 359 pages, ISBN 0 521 81859 1
8. Tutoring
contact person: Marleen Verhoye: marleen.verhoye@ua.ac.be