|Course code module||1MBMW-K-0191|
|Study load (hours)||168|
Johan Van Goethem
|Language of instruction:||Dutch|
|Semester exam information:||exam in the 1st semester|
|Contract restriction information:||exam contract not possible|
The prerequisites of 'In-vivo biomedical imaging techniques in pre-clinical and clinical context' is closely connected to the objectives of the 'Physics' course (1st Ba). Physical variables/principles which were not discussed in the course 'Physics' , and which are necessary for a good understanding of the subject matter are treated within the course.
The student must have a sufficient mathematical basic knowledge (vectors, derivatives, simple goniometrical functions, algebra, equations, solving set of equations (classical methods); basic principles of calculus (differential and integral - secondary school).
2. Objectives (expected learning outcomes)
What are you considered to know/be able at the end of this course?
You have insight in the interaction of radiation with matter and patients;
You have insight in the physical principles of different imaging techniques and their practical use in modern imaging instrumentation; you can describe these in your own words, recognize, formulate;
you have insight in the reconstruction of different image modalities and the physical parameter which is being visualized (eg. absorption, reflection, transmission, scattering, energy, radioactive decay, frequency shift, energy of nucleus in extern magnetic field, temperature,..); you can describe these in your own words, recognize, formulate;
for each of the discussed imaging techniques you can describe the origin of the image intensities; you can explain why specific tissues are represented dark or bright in the images;
you have insight how different imaging techniques can be used in a preclinical and a clinical context
3. Course content
The course discusses both the physical principles, image reconstruction and the clinical and preclinical applications of the different biomedical imaging modalities:
interaction of radiation with matter
X-ray imaging and CT-scan: instrumentation, interaction of X-radiation with matter and patients, possibilities of imaging, image reconstruction, artifacts
Echography with ultrasound: instrumentation, interaction US wave with matter, possibilities of imaging (A,B,M-mode-real time), Doppler ultrasound
Magnetic Resonance Imaging: instrumentation, origin of the MR signal, image contrast, image reconstruction
Radionuclide imaging: scintigraphy, SPECT and PET, radioactivity and detectors
During the practical demonstrations
(MRI,CT,US,PET), students are given a first introduction to the operation of the different imaging modalities used for biomedical imaging and research on animals and patients.
4. Teaching method
Direct contact: LecturesPractical sessions
Personal work: Assignments - individualPaper - individual
5. Assessment method
Exam: Written, without oral presentationOral, with written preparationMultiple choiceOpen questions
Written assignment: Without oral presentation
6. Compulsory reading – study material
An electronic version of the presentations can be downloaded from Blackboard. A print out of the presentations (2 hand-out/page) can be bought at the reprography of the University of Antwerp.
7. Recommended reading - study material
Medical Imaging Physics, 4th ed. William R. Hendee, E. Russell Ritenour, ed. Wiley-Liss, 2002 , NY-ISBN 0-471-38226-4
Fundamentals of Medical Imaging, Paul Suetens
Publisher: Cambridge University Press; Bk&CD-Rom edition (March 2002)
MRI From picture to proton, Donald W. McRobbie, Elizabeth A. Moore, Martin J. Graves, Martin R. Prince,
Publisher: CambridgeUniversity Pres, ISBN 0-521-68384-X paperback
Radiobiology for the Radiologist, 6th ed. Eric J. Hall, Amato J. Giacca
Lippincott Williams & Wilkins, 2006, ISBN 0781741513
You can always ask the teacher questions after or during the pause of a contact moment.