Laboratory Animal Science

Academic year: 2008-2009 Course code module 2MBMW-V-001 Semester: 1st semester Credits: 12 Study load (hours) 336 Theory (hours): 60,00 Practice/Exercises(hours): 20,00 Other (hours): 24,00 Part-time program: 1 Instructor(s) Peter De Deyn Christa Van Ginneken Language of instruction: Dutch Semester exam information: exam in the 1st semester Contract restriction information: exam contract not possible 1. Prerequisites *Algemene competenties The student should have a at least a bachelor's degree in one of the various biological or biomedical sciences. *Sequentiality 2. Objectives (expected learning outcomes) The course aims at teaching the students how to make optimal and scientifically founded use of animals in biomedical research and how this kind of research is conducted in accordance with Belgian and European legislation. The necessary practical skills will be taught. In addition and overview of various kinds of animal models and alternatives will be given and some of them will be discussed in detail. 3. Course content This course covers the various topics that are mentioned in the KB 13/09/2004 and which are necessary to obtain a certificate that is comparable with a felasa C degree. In short, various lectures address more general topics such as history of animal experimentation and legislation, ethics, law, other deal with vary 'practical' subjects such as nutrition, housing, anaesthesia, ... . In the last partim the definition, validity, use and restrictions of various animal models will be addressed. Representative models for (toxicologic, cardiovascular, gastrointestinal, oncologic etc) human diseases will be discussed. During the practical sessions, the students learn how to handle various lab animals and learn how the perform simple experimental techniques. When possible, alternative methods will be used. 4. Teaching method Direct contact: Lectures Seminars (possible question and answer sessions) Practical sessions Skills training Personal work: Excursion(s) Project-based work - in group 5. Assessment method Exam: Written, without oral presentation Closed book Open questions Written assignment: With oral presentation Presentation 6. Compulsory reading – study material - handouts and notes during the lectures in addition to the syllabus. 7. Recommended reading - study material -The ethics of animal and human experimentation. P.P. De Deyn et al. eds., J. Libbey Publishers, London 1994.; -Proefdieren en dierproeven. L.F.M. van Zutphen, V. Baumans, A.C. Beynen, Elsevier/Bunge, Maarssen, 1998 - J Hau & G.L. Van Hoosier Jr, ‘Handbook of Laboratory Animal Science – volume 1: Essential Principles and Practices’ 2 editie, CRC Press, 2003: 0-8493-1086-5 - J Hau & G.L. Van Hoosier Jr, ‘Handbook of Laboratory Animal Science – volume 2: Animal models’ 2 editie, CRC Press, 2003: 0-8493-1084-9 - J Hau & G.L. Van Hoosier Jr, ‘Handbook of Laboratory Animal Science – volume 3: Animal models’ 2editie, CRC Press, 2003: 0-8493-1893-9 - Gispen W.H. ‘Neuroscience Research Communications – special issue: Animal models of Neurologic and Psychiatric Disorders’, volume 26, mei/juni 2000, nummer 3. 8. Tutoring via BB prof. C. Van Ginneken: chris.vanginneken@ua.ac.be prof. PP. De Deyn: peter.dedeyn@ua.ac.be laatste aanpassing: last update: 10/09/2008 14:16 chris.vanginneken