Pharmaceutical applications of molecular biology

Academic year: 2010-2011 Course code module 1MFAR-GO-005 Semester: 2nd semester Credits: 4 Study load (hours) 112 Theory (hours): 30,00 Practice/Exercises(hours): Other (hours): Part-time program: 1 Instructor(s) Anne-Marie Lambeir Language of instruction: Dutch Semester exam information: exam in the 2nd semester Contract restriction information: 1. Prerequisites *Algemene competenties Knowledge of basic biochemistry and pharamceutical biotechnology is required. *Sequentiality Biochemistry (2BFAR-04) AND Pharmaceutical Biotechnology (3BFAR-07) 2. Objectives (expected learning outcomes) Obtain insights in the rationale and the strategies of molecular biology in research, development and production of medicinal compounds. 3. Course content This course follows the bachelor course "Pharmaceutical Biotechnology". The student continues to explore methods of molecular biology used in the fields of drug development and molecular diagnostics. The student learns how to retrieve useful information from public data bases containing DNA and protein sequences and to analyse these data with bioinformatics. Exercises are provide on the analysis of protein structures and the interactions between drugs and their target proteins. Theoretical classes provide background on the structure and maps of the human genome and single-gene disorders. We also discuss a number of techniques for the study of gene expression and proteomics. 4. Teaching method Direct contact: Lectures Exercise sessions Personal work: Exercises Assignments - individual Assignments - in group Supervised self-study 5. Assessment method Exam: Oral, with written preparation Open book Continuous assessment: Assignments Participation in classroom activities Written assignment: Without oral presentation 6. Compulsory reading – study material Human Molecular genetics, 3rd Ed. Peter Sudbery, Ian Sudbery. Pearson Education 2009, ISBN; 978-0-132-05157-6 7. Recommended reading - study material 8. Tutoring Contact: anne-marie.lambeir@ua.ac.be laatste aanpassing: last update: 26/01/2011 10:42 anne-marie.lambeir