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Course descriptions

Laboratory Animal Science
Course Code :2005FBDBMW
Study domain:Biomedical Sciences
Semester:Semester: 1st semester
Contact hours:104
Credits:12
Study load (hours):336
Contract restrictions: Exam contract not possible
Language of instruction :English
Exam period:exam in the 1st semester
Tutor(s)Peter De Deyn
Chris Van Ginneken
Debby Van Dam

 

1. Prerequisites

At the start of this course the student should have acquired the following competences:
An active knowlegde of :
  • English
A passive knowledge of :
  • English
  • General knowledge of the use of a PC and the Internet
Specific prerequisites for this course:
A bachelors' degree in one of the life sciences.
Students with differing degree should contact the course organization in order to obtain an alternative program.

The course is open to foreign students which can take the course as a separate module or as part of emmi (european master in molecular imaging). Funding of these students can be provided (an intensive programme is granted by eu). 


2. Learning outcomes

The course aims at teaching the students how to make optimal and scientifically founded use of animals in biomedical research and how this kind of research is conducted in accordance with Belgian and European legislation. The necessary practical skills will be taught. In addition and overview of various kinds of animal models and alternatives will be given and some of them will be discussed in detail. 
The student is able to analyze a biomedical question, and can formulate a research strategy that uses animal experiments cf the state of the art (eg. 3R, according to European directives and Belgian law, according to the ethical dossiers). The student can communicate in writing and orally in Dutch and English about these animal experimentation. He / she can reflect on the social and ethical implications of animal studies and has a lifelong learning attitude developed in order to follow up on the evolutions in this domain.


3. Course contents

This course covers the various topics that are mentioned in the KB 13/09/2004 and which are necessary to obtain a certificate that is comparable with a felasa C degree. In short, various lectures address more general topics such as history of animal experimentation and legislation, ethics, law, other deal with vary 'practical' subjects such as nutrition, housing, anaesthesia, ... . In the last partim the definition, validity, use and restrictions of various animal models will be addressed. Representative models for (toxicologic, cardiovascular, gastrointestinal, oncologic etc) human diseases will be discussed. During the practical sessions, the students learn how to handle various lab animals and learn how the perform simple experimental techniques. When possible, alternative methods will be used. 

4. Teaching method

Class contact teaching:
  • Lectures
  • Practice sessions
  • Seminars
  • Tutorials
  • Laboratory sessions
  • Skills training

    • Personal work:
  • Assignments:Individually
  • Assignments:In group
  • Casussen: In group
  • Paper: In group

    • Excursions
    Project-based work:
  • In group


    • 5. Assessment method and criteria

    Examination:
  • Written without oral presentation
  • Closed book
  • Open-question

    • Continuous assessment:
  • Exercises
  • Assignments
  • Case studies
  • Participation in classroom activities

    • Presentation
    6. Study material

    Required reading

    - handouts

    Optional reading

    The following study material can be studied on a voluntary basis:

    - P.P. De Deyn et al. eds., 'The ethics of animal and human experimentation', J. Libbey Publishers, London 1994
    - L.F.M. van Zutphen, V. Baumans, A.C. Beynen, 'Proefdieren en dierproeven', Elsevier/Bunge, Maarssen, 1998
    - J Hau & G.L. Van Hoosier Jr, ‘Handbook of Laboratory Animal Science – volume 1: Essential Principles and Practices’ 2 editie, CRC Press, 2003: 0-8493-1086-5
    - J Hau & G.L. Van Hoosier Jr, ‘Handbook of Laboratory Animal Science – volume 2: Animal models’ 2 editie, CRC Press, 2003: 0-8493-1084-9
    - J Hau & G.L. Van Hoosier Jr, ‘Handbook of Laboratory Animal Science – volume 3: Animal models’ 2editie, CRC Press, 2003: 0-8493-1893-9
    - Gispen W.H. ‘Neuroscience Research Communications – special issue: Animal models of Neurologic and Psychiatric Disorders’, volume 26, mei/juni 2000, nummer 3. 

    7. Contact information
    chris.vanginneken@ua.ac.be  
    (+)last update: 02/07/2012 12:43 chris.vanginneken  
     
    Inhoudsverantwoordelijke(n) : chris.vanginneken