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1. Prerequisites

At the start of this course the student should have acquired the following competences:

• Competences corresponding the final attainment level of secondary school

An active knowlegde of :

• Dutch

Specific prerequisites for this course:

The prerequisites of Radio protection and introduction to medical imaging ' is closely connected to the objectives of the 'Physics' course (1st Ba). Physical variables/principles which were not discussed in the course 'Physics' , and which are necessary for a good understanding of imaging techniques and radioprotection are treated within the course.

The student must have a sufficient mathematical basic knowledge (vectors, derivatives, simple goniometrical functions, algebra, equations, solving set of equations (classical methods); basic principles of calculus (differential and integral - secondary school).

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2. Learning outcomes

What are you considered to know/be able at the end of this course?

 

imaging

• You have insight in the interaction of radiation with matter;
• You have insight in the physical principles of different imaging techniques and their practical use in modern imaging instrumentation; you can describe these in your own words, recognize, formulate;
• you have insight in the reconstruction of different image modalities and the physical parameter which is being visualized (eg. absorption, reflection, transmission, scattering, energy, radioactive decay, frequency shift, energy of nucleus in extern magnetic field, temperature,..); you can describe these in your own words, recognize, formulate;
• for each of the discussed imaging techniques you can describe the origin of the image intensities; you can explain why specific tissues are represented dark or bright in the images;

 

radioprotection

• You have knowledge of radioactivity, what is ionizing radiation ( (α-, β-, γ-, en X-radiation) and how do they i nteract with matter;
• you have insight in de different methods to measure ionizing radiation, thorough knowledge of the detectors and/or measure methods, the units in which radiation doses are given (dosimeter);
• you have knowledge of the biological impact of ionizing radiation (at molecular (DNA), cellular, tissular and organic level) and insight in the distinct deterministical and stochastical effects
• you are familiar with the basic principles of radioprotection (justification, optimalisation and dose limitation) en have command of the elementary radioprotection proceedings (distance, time, shielding);
• you have basic knowledge of Radioecology (natural and artificial  radioactivity, transfer modalities and kind of contamination), including sufficient knowledge of the radiological bio-indicators;
• you have insight in the radiological emergence- and contingency plan especially focussed on the proceedings in the agro sector and the cattle breeding (protection of the food chain), yet without excluding the plan with respect to small pet(animals);
• you have insight in and are familiar with the rules and law regarding ionizing radiation (National: ARBIS, K.B. of 20 juli 2001, European: Guidelines, International: ICRP-documents).

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3. Course contents

part1: Marleen Verhoye

The course discusses both the physical principles, image reconstruction and the clinical and preclinical applications of the different biomedical imaging modalities:

1.     interaction of radiation with matter

2.     X-ray imaging and CT-scan: instrumentation,  interaction of X-radiation with matter and patients, possibilities of imaging, image

3.     Echography with ultrasound: instrumentation, interaction US wave with matter, possibilities of imaging (A,B,M-mode-real time), Doppler ultrasound

4.     Magnetic Resonance Imaging: instrumentation, origin of the MR signal, image contrast, image reconstruction (limited)

5.     radioactivity: radioactive radiation, variables, units and radioactive decay

 

part 2: Ivan Huyghe

1.       biological aspecs of ionizing radiation

2.       dosimetry: Why is it needed? How where the proceedings historically created, and how are they adapted?

3.       rules and law regarding ionizing radiation is discussed from a practical point of view

4.       detectors: low doses; gamma-camera/PET

5.       tracers: generator concept (Molybdeen–Technetium) examples of tracers actually used in veterinary; 

6.       Radionuclide imaging: planar scintigraphy, SPECT and introduction to PET and fusion techniques (PET-CT and SPECT-CT)

7.       Therapy with Jodium 131

 

 

The practical sessions ( MRI (Bio-Imaging Lab)/ CT- PET (MICA)/US (Fysiologie)) ) gives the student a first introduction to the operation of the different imaging modalities used for biomedical imaging.

 

For each practical session, students will make a groups report (4 students per report)

-           1 scientific groups report :objective, materials and methods, image processing and results, conclusion.

-           clearly indicating the names of all group members

-           the written (critical) part of the practice report is limited to 3 pages.. so without images.

-           The report (Word document) is mailed to M. Verhoye (marleen.verhoye@ua.ac.be), or upload via BB the latest, to be decided

 

 

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4. Teaching method

Class contact teaching:

Lectures

Laboratory sessions

Personal work:

Assignments:In group

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5. Assessment method and criteria

Examination:

Oral with written preparation

Open-question

Continuous assessment:

Assignments

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6. Study material

Required reading

 

Course documents

An electronic version of the presentations can be downloaded from Blackboard. A print out of the presentations (2 hand-out/page) can be bought at the reprography of the University of Antwerp.

Optional reading

The following study material can be studied on a voluntary basis:

Medical Imaging Physics, 4th ed. William R. Hendee, E. Russell Ritenour, ed. Wiley-Liss, 2002 , NY-ISBN 0-471-38226-4

 

Fundamentals of Medical Imaging, Paul Suetens
Publisher: Cambridge University Press; Bk&CD-Rom edition (March 2002)
ISBN: 0521803624

 

MRI From picture to proton, Donald W. McRobbie, Elizabeth A. Moore, Martin J. Graves, Martin R. Prince,

Publisher: CambridgeUniversity Pres, ISBN 0-521-68384-X paperback

 

Radiobiology for the Radiologist, 6^th ed. Eric J. Hall, Amato J. Giacca

Lippincott Williams & Wilkins, 2006, ISBN 0781741513

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7. Contact information

Dr. Marleen Verhoye
Bio-Imaging Lab

University of Antwerp, Campus Drie Eiken (CDE)

Universiteitsplein 1,

building Uc, room 1.12
B-2610 Antwerp (Wilrijk)
Belgium
Tel:       ++ 32 (0)3 2652786 

            ++ 32 (0)3 2652780
email: Marleen.Verhoye@ua.ac.be

http://webhost.ua.ac.be/biomag/

(+)last update: 04/10/2011 15:23 marleen.verhoye